General Microbiology Historical Introduction Question And Answers

Historical Introduction Important Notes

1. Scientists And Their Contribution

Historical Introduction Scientists And Their Contribution

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2. Staining

Historical Introduction Staining

Historical Introduction Short Answers

Question 1. Koch’s postulates/Robert Koch?
Answer:

. Koch’s Postulates/Robert Koch

  • Robert Koch is known as the father of medical microbiology.
  • His contributions to microbiology are:

1. Robert Koch Introduced

  • Methods of obtaining bacteria in pure cultures using solid media.
  • Staining techniques for bacteria
  • Methods for isolation of pure strains of bacteria.

2. Robert Koch Discovered

  • Anthrax bacillus
  • Tubercle bacillus
  • Cholera vibrios.

3. Robert Koch Proposed Koch’s Postulates

  • Koch’s Postulates:
    • According to Koch’s postulates, a micro-organism can be accepted as the causative agent of an infectious disease only if
      • The organism is constantly associated with the lesions of the disease
      • If it is possible to isolate the organism in pure cultures from the lesions of the disease.
      • Inoculation of such pure culture into suitable laboratory animals will reproduce the lesions of the disease.
      • If it is possible to re-isolate the bacterium in pure culture from the lesions produced in the experimental animals.

4. He Demonstrated Koch’s Phenomenon Through His Observation Of Guinea Pigs

  • It Is As Follows
    • Koch’s Phenomenon:
      • Robert Koch observed that guinea pigs already infected with tubercle bacillus responded with an exaggerated inflammatory response when injected with the tubercle bacillus (or) its protein.
      • This hypersensitivity reaction is known as Koch’s phenomenon.

Question 2. Louis Pasteur.
Answer:

Louis Pasteur

  • He was a trained chemist in France.
  • He is known as the father of microbiology.

General Microbiology Microbiology

Important Contributions In Microbiology:

  • He developed methods and techniques of bacteriology.
  • Introduced sterilization techniques.
  • Developed steam sterilizer, autoclave, and hot air oven
  • Developed live attenuated vaccine for prophylactic use
  • He studied
    • Chicken cholera
    • Anthrax
    • Hydrophobia
  • He also coined the term vaccine.
  • He proved that all forms of life even microbes arose only from their like and not de novo.
  • He proposed a microbial theory of fermentation to explain the role of microorganisms in disease production
  • He controlled the diseases of silkworm

 

 

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