Oral Medicine Aids Important Notes
1. Drugs Used In The Management Of AIDS
- Azidothymidine
- Pentamidine
- Didanosine
2. Hairy Leukoplakia
- Hairy Leukoplakia is HIV associated oral lesion
- Hairy Leukoplakia is nonmalignant
- The site involved: lateral border of the tongue
- Hairy Leukoplakia appears as vertical white folds
Oral Medicine Aids Short Essays
Question 1. Oral manifestations of HIV.
Answer:
Oral Manifestations Of HIV
- Candidiasis
- Erythematous
- Hyperplastic
- Pseudomembranous
- Oesophageal
- Herpes Simplex infection
- Herpes Zoster infection
- Hairy leukoplakia
- Kaposi’s sarcoma
- Angular cheilitis
- HIV-gingivitis
- HIV-periodontitis
- Necrotizing ulcerative gingivitis
- Necrotizing stomatitis
- Major aphthae
- Vesiculobullons lesion
- Parotitis
Read And Learn More: Oral Medicine Question and Answers
- Toxoplasmosis
- Purpura
- Osteomyelitis
- Acute non-specific ulcers
- Cytomegalo virus infection
- Human papillomavirus infection
- Squamous cell carcinoma
- Lymphoma
- Xerostomia
- Facial palsy
- Trigeminal neuropathy
- Submandibular cellulitis
- Delayed wound healing
- Tuberculous ulcers
- A typical oropharyngeal ulceration
- Bacillary angiomatosis
- Addisonian pigmentation
- Unilateral or bilateral swelling of the salivary gland.
Question 2. Laboratory diagnosis of HIV.
(or)
Two investigations into HIV infections
Answer:
1. Elisa (Enzyme-Linked Immunosorbent Assay):
- Elisa is a color reaction test
Elisa Method:
- A serum containing antibodies is developed from the patient’s blood sample
- It is added to the ELISA plate
- Wash off the inactive antibodies
- A second layer of antibodies, called a conjugate is added
- Excess antibodies are again washed off
- A substrate (chromogen) is added to it.
Elisa Result:
- Color becomes a darker positive test
- No color change – Negative test
2. Western Blot:
Western Blot Method:
- Viral proteins from the patient’s blood sample are passed through a gel
- The separated proteins are then passed through an electric current
- Human serum is added
- A chromogen is added to it
Western Blot Result:
- A specific band of viral protein is detected.
Oral Medicine Aids Viva Voce
- An initial opportunistic infection in AIDS patients is pneumocystis carinii pneumonia
- AIDS patients become susceptible to infection when the T4 lymphocyte count is below 50 mm3
- A major target of HIV infection are the immune system and central nervous system
- Kaposi sarcoma is the most common neoplastic disease of AIDS
- Non-Hodgkin’s disease is the most rapidly increasing malignant disease of AIDS